Study OEV-123 – Phase IIb Safety, diagnostic methodology evaluation and estimated vaccine efficacy in travellers to Benin

A randomised, placebo controlled, double blinded phase 2b study was conducted in 743 Finnish tourists, between the ages of 18 to 65 years of age, travelling to Benin. The objectives were to evaluate safety and tolerability, new diagnostical methodology and establish preliminary vaccine efficacy.

The incidence of TD was >60%; ETEC was the most common pathogen; the vaccine was safe and well tolerated and the strain coverage offered by the vaccine was approximately 90%. All samples from the clinical trial are now being analysed and will be unblinded and presented Q1 2020.

This study is co funded by SME Instrument, part of the EU’s Horizon 2020 research and Innovation programme.