Study OEV-120 – Phase I, Safety and immunogenicity of a prototype vaccine

The safety and immunogenicity of a prototype vaccine was compared to a previously developed oral ETEC vaccine in a randomized clinical Phase I trial in 60 Swedish volunteers. The volunteers were given two oral doses of either the prototype or the reference vaccine. The prototype vaccine was found to be as safe and equally well […]

Study DMID 09-066 – Phase I, dmLT adjuvant safety and immunogenicity

The dmLT adjuvant was studied in a dose-escalation clinical phase-I trial evaluating safety and immunogenicity of a single oral administration. The dmLT was safe and well tolerated by the 36 study participants. The study was conducted under an US IND. SS. El-Kamary, 2013. Safety and immunogenicity of a single oral dose of recombinant double mutant […]